Part I: Biologic Principles and Interactive Jaw Mechanics : Section 1: Form and Function. -- • Development of Mandibular Form: Phylogeny, Ontogeny, and Function. -- • Morphology and Mechanism of the Jaw Joint. -- • Jaw Muscle Structure and Function. -- • Neural Control of Oral Behavior and Its Impact on Occlusion. -- • The Dynamics of Occlusal Relationships. -- • The Supporting Structures and Dental Adaptation. -- Section 2: Growth and Development. -- • Effect of Function on Growth and Remodeling of the Temporomandibular Joint. -- • Macromolecular Components of Connective Tissues and Their Roles in Determining Tissue Mechanical Properties. -- • Effect of the Physical Environment on Growth of the Temporomandibular Joint. -- • Relationship Between Growth, Function, and Stress in the Temporomandibular Joint. -- • Adaptive Changes in Mandibular Muscles During Postnatal Development. -- Section 3: Biomechanics. -- • Engineering Principles and Modeling Strategies. -- • In Vivo Bone Strain Patterns in the Craniofacial Region of Primates. -- • Simulated Physics of the Human Mandible. -- • Computer Simulations of Jaw Biomechanics. -- • Biomechanical and Biomaterial Considerations of Root-Form Dental Implants. -- Section 4: Tissue Response -- Connective Tissue Response to Mechanical Stimulation. -- • Disc Displacement Internal Derangements. -- • Biology of TMJ Degeneration: The Role of Matrix-Degrading Enzymes. -- • Distribution of Local and General Stresses in the Stomatognathic System. -- Part II: Clinical Considerations for a Favorable Tissue Response. -- Section 5: Decision-making and Biologically Based Treatment Goals. -- • Maxillomandibular Relationships: Mandibular Asymmetry, Occlusion, and Imaging. -- • Clinical Decision-making in Occlusion: A Paradigm Shift. -- • Fundamental Treatment Goals. -- Section 6: Baseline Records and Diagnostic Tests. -- • History and Examination. -- • Mounted Study Casts and Cephalometric Analysis. -- • Maxillofacial Imaging. -- • Jaw Tracking and Temporomandibular Joint Animation. -- Section 7: Problem Solving and Treatment Planning. -- • Interocclusal Appliances: Do They Offer a Biologic Advantage?. -- • Role of Occlusion in Periodontal Disease. -- • Selective Tooth Grinding and Equilibration. -- • Fundamental Occlusal Therapy Considerations. -- Section 8: Restorative and Prosthodontic Therapy. -- • Occlusal Considerations for Complex Restorative Therapy. -- • Occlusal Considerations in Complete Dentures. -- • Masticatory Performance Measures for Maxillofacial Prosthodontics. -- • Occlusion and Crestal Bone Resorption: Etiology and Treatment-Planning Strategies for Implants. -- Section 9: Orthodontic and Related Surgical Therapy. -- • Long-term Stability of Mandibular Orthopedic Repositioning. -- • Gnathologic Considerations for Orthodontic Therapy. -- • Occlusal Considerations for Orthognathic Surgery.

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